Overview
Dihexa is a research-grade peptide compound that has attracted significant attention in the scientific community for its role in cellular and anti-aging. Angiotensin IV analog. Studied for extraordinary neurotrophic potency — up to 10⁷× more active than BDNF in promoting synaptic connectivity.
This compound belongs to the cellular category of research peptides and has been the subject of numerous preclinical investigations. Its unique molecular properties make it a valuable tool for researchers exploring novel therapeutic pathways.
Dihexa (N-hexanoic-Tyr-Ile-(6) aminohexanoic amide) is a stable, blood-brain-barrier-penetrant analog of angiotensin IV. It activates hepatocyte growth factor (HGF/c-Met) signaling, promoting dendritic spine formation and synaptic connectivity. In animal models, it demonstrated neurotrophic factor expression at picomolar concentrations — orders of magnitude more potent than BDNF. The growing body of published literature continues to expand our understanding of this compound's potential applications in laboratory settings.
Mechanism of Action
Dihexa (N-hexanoic-Tyr-Ile-(6) aminohexanoic amide) is a stable, blood-brain-barrier-penetrant analog of angiotensin IV. It activates hepatocyte growth factor (HGF/c-Met) signaling, promoting dendritic spine formation and synaptic connectivity. In animal models, it demonstrated neurotrophic factor expression at picomolar concentrations — orders of magnitude more potent than BDNF.
The signaling pathways activated by Dihexa continue to be mapped through proteomic and transcriptomic analyses. Current research focuses on identifying the specific receptor subtypes and downstream effectors responsible for the observed biological responses. Understanding these molecular interactions is critical for advancing the compound from preclinical investigation toward potential translational applications.
Research Areas
- Telomere biology and cellular aging
- Mitochondrial function optimization
- Oxidative stress resistance
- Circadian rhythm regulation
- Cellular senescence pathways
Compound Specifications
| CAS Number | 1401708-83-5 |
| Purity | ≥98% HPLC verified |
| Storage | −20 °C, protect from light and moisture. |
| Category | Cellular Maintenance |
| Price | €65 |
| Format | 10mg lyophilised |
Available Formats
- 5mg vial
- 10mg vial
Dissolution
Use our dilution calculator for precise concentration calculations.