Overview
NAD+ is a research-grade peptide compound that has attracted significant attention in the scientific community for its role in cellular and anti-aging. Nicotinamide adenine dinucleotide. Essential coenzyme studied for cellular energy metabolism, DNA remodeling, and sirtuin-mediated cellular maintenance pathways.
This compound belongs to the cellular category of research peptides and has been the subject of numerous preclinical investigations. Its unique molecular properties make it a valuable tool for researchers exploring novel therapeutic pathways.
NAD+ is a central coenzyme in redox metabolism, serving as an electron carrier in glycolysis, the TCA cycle, and oxidative phosphorylation. It is also a required substrate for sirtuins (SIRT1–7), PARPs, and CD38 — enzymes governing DNA remodeling, epigenetic regulation, and circadian modulation. Intracellular NAD+ declines with age; supplementation studies show restoration of mitochondrial function and activation of cellular maintenance gene networks. The growing body of published literature continues to expand our understanding of this compound's potential applications in laboratory settings.
Mechanism of Action
NAD+ is a central coenzyme in redox metabolism, serving as an electron carrier in glycolysis, the TCA cycle, and oxidative phosphorylation. It is also a required substrate for sirtuins (SIRT1–7), PARPs, and CD38 — enzymes governing DNA remodeling, epigenetic regulation, and circadian modulation. Intracellular NAD+ declines with age; supplementation studies show restoration of mitochondrial function and activation of cellular maintenance gene networks.
The signaling pathways activated by NAD+ continue to be mapped through proteomic and transcriptomic analyses. Current research focuses on identifying the specific receptor subtypes and downstream effectors responsible for the observed biological responses. Understanding these molecular interactions is critical for advancing the compound from preclinical investigation toward potential translational applications.
Research Areas
- Telomere biology and cellular aging
- Mitochondrial function optimization
- Oxidative stress resistance
- Circadian rhythm regulation
- Cellular senescence pathways
Compound Specifications
| CAS Number | 53-84-9 |
| Purity | ≥98% enzymatic grade |
| Storage | −20 °C lyophilised. Protect from light and moisture. |
| Category | Cellular Maintenance |
| Price | €85 |
| Format | 500mg lyophilised |
Available Formats
- 250mg vial
- 500mg vial
- 1g vial
Dissolution
Use our dilution calculator for precise concentration calculations.